Letrozol is an anti-estrogen like exedrol, which is used as a secondary solution when breast cancer treatment with tamoxifen does not work. Each pill contains 2.5 milligrams of active ingredient that reduces estrogen levels by 78%. Unwanted effects of this estrogen are that causes the decrease of good cholesterol in the blood. This is because estrogen is linked with blood cholesterol and estrogen inhibition leads to a decrease of good cholesterol in the blood. Tamoxifen and Clomed are going to keep good cholesterol in the blood because they are active estrogen in the liver. This antiestrogen is used if you want to obtain the strongest muscles and striated appearance. Optimal dose is a half of tablet per day for better results can be taken one pill per day.